| 书目名称 | Mechanisms of Physical and Emotional Stress |
| 编辑 | George P. Chrousos,D. Lynn Loriaux,Philip W. Gold |
| 视频video | |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | It has been over 50 years since Hans Selye formulated his concept of stress. This came after the isolation of epinephrine and norepinephrine and after the sympathetic system was associated with Walter Cannon‘s "fight or flight" response. The intervening years have witnessed a number of dis coveries that have furthered our understanding of the mechanisms of the stress response. The isolation, identification and manufacture of gluco corticoids, the identification and synthesis of ACTH and vasopressin, and the demonstration of hypothalamic regulation of ACTH secretion were pivotal discoveries. The recent identification and synthesis of CRR by Willie Vale and his colleagues gave new impetus to stress research. Several new concepts of stress have developed as a result of advances in bench research. These include the concept of an integrated "stress sys tem", the realization that there are bi-directional effects between stress and the immune system, the suggestion that a number of common psychiatric disorders represent dysregulation of systems responding to stress, and the epidemiologic association of stress with the major scourges of humanity. |
| 出版日期 | Book 1988 |
| 关键词 | CNS; behavior; biology; pharmacology; regulation; reproduction |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4899-2064-5 |
| isbn_softcover | 978-1-4899-2066-9 |
| isbn_ebook | 978-1-4899-2064-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
发表于 2025-3-21 17:30:13
