书目名称 | Mechanisms of Lymphocyte Activation and Immune Regulation VI |
副标题 | Cell Cycle and Progr |
编辑 | Sudhir Gupta,J. John Cohen |
视频video | |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | Since programmed cell death was first described in insects in 1964 and apoptosis was described in 1972, rapid progress has been made in understanding the basic mechanisms and genes regulating programmed cell death and apoptosis. In addition, defects in various genes regulating programmed cell death have been delineated in several experimental models of human diseases. This volume surveys various aspects of these rapidly developing areas of research in programmed cell death/apoptosis. This volume should be of interest to basic immunologists and molecular biologists. The volume begins with a historical perspective of cell death. The remainder of the volume is divided into four different parts. Part I deals with the signaling pathways in apoptosis, including cell cycle control of apoptosis, role of ceramide in apoptosis, role of antibody signaling, and biochemical regulation of apoptosis. The mechanisms for recognition of apoptotic lymphocytes by macrophages are also reviewed. Part II examines the role of various genes that regulate apoptosis, including the role ofFas, FasL, and other TNF family members in apoptosis and homeostatic regulation of immune response. Recently described spl |
出版日期 | Book 1996 |
关键词 | T cell; Thymus; apoptosis; diseases; insects; lymphocytes; macrophages; programmed cell death; proteins; viru |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4899-0274-0 |
isbn_softcover | 978-1-4899-0276-4 |
isbn_ebook | 978-1-4899-0274-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |