Titlebook: Mechanisms of Invasion in Cancer; Pierre Denoix Conference proceedings 1967 Springer-Verlag Berlin · Heidelberg 1967 cancer

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The Tumour Cell and Vascular Bed Size Relationship in Experimental Metastases,have been observed to increase incidence of metastases; heparin (Agostino, 1962; Gallinotto, 1964) fibrinolysin (Grossi, 1960) chymotrypsin (Cagliani, 1962) neuraminidase (Gasic, 1962) coumadin (Agostino, 1963) surgery (Ketcham, 1961) and x-irradiation of donor (Hoye, 1961) have been observed to red

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The Significance of Pericarcinomatous Metastases in Local Growth,s following necrobiotic processes. Even under physiological conditions aged and degenerated cells escape from their cell-to-cell connection and desquamate. With the progression of the tumour, ever more and increasingly viable cell beome detached from it and find their way into the surrounding tissue

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Early Invasive Growth as Seen in Uterine Cancer and the Role of the Basal Membrane,invasion” or “early stromal infiltration” (Fig. 1). It is characterized by prong-like protrusions of the surface epithelium into the stroma, comparable to the claws of a crayfish. This stage has repeatedly been used for studying at its very beginning, the infiltrating growth which is so characterist

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Some Factors Relating to the Invasiveness and Destructiveness of Solid Malignant Tumours,s and thoughts about cellular cohesion (B. and ., 1962; ., 1947), the role of ameboid movement (., 1962), contact inhibition (., 1962), cell aggregation (., 1962), surface characteristics pertaining to the locomotion of malignant cells (., 1963) and data from organ culture studies (. and ., 1963; .,

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Studies on Metastasis of Spontaneous and Transplantable Tumours at High Altitude,itted the establishment of a high-altitude laboratory in Morococha, a mining town 14,900 feet above sea level with a barometric pressure of 446 mm Hg, and with 13 per cent atmospheric oxygen. The travel time from the sea-level laboratory in Lima is less than four hours by automobile.

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The Tumour Cell and Vascular Bed Size Relationship in Experimental Metastases,or review many investigations in which varying conditions have been applied experimentally to manipulate the patterns of metastases. Of most general interest has been the manner in which intravascular spread of tumour could be controlled. To quote some examples: local injury, either chemical or phys

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Immunological Tolerance and Host-Tumour Relationship,tumour grafts. Syngeneic transplants of chemically induced tumours grow only at the site of transplantation. The non-manifestation of detectable metastases elsewhere in the organism could have been attributed to the early death of the animals caused by rapid growth of the primary implant, before met

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