书目名称 | Mechanisms of Drug Interactions | 编辑 | Patrick F. D’Arcy,James C. McElnay (Director),Pete | 视频video | | 丛书名称 | Handbook of Experimental Pharmacology | 图书封面 |  | 描述 | Over the years a number of excellent books have classified and detailed drug drug interactions into their respective categories, e.g. interactions at plasma protein binding sites; those altering intestinal absorption or bioavailability; those involving hepatic metabolising enzymes; those involving competition or antagonism for receptor sites, and drug interactions modifying excretory mechanisms. Such books have presented extensive tables of interactions and their management. Although of considerable value to clinicians, such publica tions have not, however, been so expressive about the individual mechanisms that underlie these interactions. It is within this sphere of "mechanisms" that this present volume specialises. It deals with mechanisms of in vitro and in vivo, drug-drug, drug food and drug-herbals interactions and those that cause drugs to interfere with diagnostic laboratory tests. We believe that an explanation of the mechanisms of such interactions will enable practitioners to understand more fully the nature of the interactions and thus enable them to manage better their clinical outcome. If mechanisms of interactions are better understood, then it may be pos sible f | 出版日期 | Book 1996 | 关键词 | Filtration; Wechselwirkung; absorption; amino acid; chemotherapy; drug; enzyme; enzymes; kidney; metabolism; p | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-61015-8 | isbn_softcover | 978-3-642-64658-4 | isbn_ebook | 978-3-642-61015-8Series ISSN 0171-2004 Series E-ISSN 1865-0325 | issn_series | 0171-2004 | copyright | Springer-Verlag Berlin Heidelberg 1996 |
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