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Titlebook: Mechanisms of Drug Interactions; Patrick F. D’Arcy,James C. McElnay (Director),Pete Book 1996 Springer-Verlag Berlin Heidelberg 1996 Filtr

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书目名称Mechanisms of Drug Interactions
编辑Patrick F. D’Arcy,James C. McElnay (Director),Pete
视频video
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: Mechanisms of Drug Interactions;  Patrick F. D’Arcy,James C. McElnay (Director),Pete Book 1996 Springer-Verlag Berlin Heidelberg 1996 Filtr
描述Over the years a number of excellent books have classified and detailed drug­ drug interactions into their respective categories, e.g. interactions at plasma protein binding sites; those altering intestinal absorption or bioavailability; those involving hepatic metabolising enzymes; those involving competition or antagonism for receptor sites, and drug interactions modifying excretory mechanisms. Such books have presented extensive tables of interactions and their management. Although of considerable value to clinicians, such publica­ tions have not, however, been so expressive about the individual mechanisms that underlie these interactions. It is within this sphere of "mechanisms" that this present volume specialises. It deals with mechanisms of in vitro and in vivo, drug-drug, drug­ food and drug-herbals interactions and those that cause drugs to interfere with diagnostic laboratory tests. We believe that an explanation of the mechanisms of such interactions will enable practitioners to understand more fully the nature of the interactions and thus enable them to manage better their clinical outcome. If mechanisms of interactions are better understood, then it may be pos­ sible f
出版日期Book 1996
关键词Filtration; Wechselwirkung; absorption; amino acid; chemotherapy; drug; enzyme; enzymes; kidney; metabolism; p
版次1
doihttps://doi.org/10.1007/978-3-642-61015-8
isbn_softcover978-3-642-64658-4
isbn_ebook978-3-642-61015-8Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 1996
The information of publication is updating

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Book 1996 plasma protein binding sites; those altering intestinal absorption or bioavailability; those involving hepatic metabolising enzymes; those involving competition or antagonism for receptor sites, and drug interactions modifying excretory mechanisms. Such books have presented extensive tables of inte
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Drug-Food Interactions Affecting Drug Absorptioninclude drug-drug interactions and also drug-food interactions. After examining the quantity of material that has been published on these two closely related but distinct topics, it was agreed that drug-drug interactions and drug-food interactions affecting drug absorption would be better presented in two separate chapters.
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In Vitro Drug Interactionsof a drug with its packaging (e.g., drug binding to an infusion bag), due to loss of drugs during laboratory analyses (e.g., binding to laboratory equipment) or due to changes in the bioavailability of drugs when the formulation is altered (McElnay and D’Arcy 1980).
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