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Titlebook: Mechanisms of Cell-Mediated Cytotoxicity; William R. Clark,Pierre Golstein Book 1982 The Editor(s) (if applicable) and The Author(s), unde

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书目名称Mechanisms of Cell-Mediated Cytotoxicity
编辑William R. Clark,Pierre Golstein
视频video
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Mechanisms of Cell-Mediated Cytotoxicity;  William R. Clark,Pierre Golstein Book 1982 The Editor(s) (if applicable) and The Author(s), unde
描述The First International Workshop on Mechanisms in Cell-Mediated Cytoxicity was held at Carry-Ie-Rouet, France, September 14-16, 1981. The Workshop brought together for the first time leading investiga­ tors in each of the principal areas of cell-mediated cytotoxicity, as well as experts in the area of complement-mediated cytoxicity. Formal research presentations were held to a minimum, the emphasis being on open discussion of current knowledge about mechanisms of cytoxicity in each of the systems under consideration. The major objectives of the Workshop were 1) to compare and integrate what is known about the mechanism(s) of cytoxicity in each system; 2) to determine whether, on the basis of information in hand, it seems likely that the mechanisms of cytotoxicity in the various systems are the same or are unique; and 3) to stimulate thinking about new approaches to elucidating the fundamental mechanisms by which certain cells are able to kill other cells.
出版日期Book 1982
关键词T cell; antibody; antigen; cells; cytotoxicity; genetics; growth factor; hand; lymphocytes; research; thinking
版次1
doihttps://doi.org/10.1007/978-1-4684-8959-0
isbn_softcover978-1-4684-8961-3
isbn_ebook978-1-4684-8959-0Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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T Lymphocyte-Mediated Cytolysis — A Comprehensive Theory I. The Mechanism of CTL-Mediated Cytolysisd other proposed mechanisms have been extensively reviewed (see ref. 10–13). Despite a great deal of imaginative experimentation in pursuit of these various hypotheses, none of them has attracted widespread support as a principle mechanism of CTL-mediated cytolysis.
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T Lymphocyte-Mediated Cytolysis — A Comprehensive Theory II. Lytic vs. Nonlytic Interactions of T Ly,3 CTL bear receptors for K/D antigens, whereas Ly 2,3 suppressor cells have receptors for determinants coded for by genes in the I-J subregions. Ly 1 T cells do not normally function as CTL; whether Ly 2,3 suppressor T cells utilize a cytotoxic mechanism in their function is uncertain.
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Direct Analysis of Individual Killer T Cells: Susceptibility of Target Cells to Lysis and Secretion a soluble mediator secreted by the killer lymphocytes (8). C) Cytolysis which does not require the continuous presence of the effector cell. The target cell undergoes a series of membrane permeability alterations leading to cell destruction (5–7).
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Gideon Berke,William R. Clark the political responses to the global health crisis experienced since 2020. But what is common to all these crises is the reinforcement of the historic and seemingly inextricable link between global cities and mega-events of which the Games are the most iconic embodiment. This historical approach w
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