书目名称 | Mechanisms of Anesthetic Action in Skeletal, Cardiac, and Smooth Muscle | 编辑 | Thomas J. J. Blanck,David M. Wheeler | 视频video | | 丛书名称 | Advances in Experimental Medicine and Biology | 图书封面 |  | 描述 | The volatile anesthetics continue to be one of the most mysterious yet commonly used class of drugs in medical practice today. A prominent and troublesome side effect of volatile anesthetics is their ability to alter hemodynamics. This arises from two diverse but interrelated phenomena, depression of cardiac contractility and dilation of the vasculature. These effects of volatile anesthetics on cardiac and smooth muscle plus the action of volatile anesthetics on skeletal muscle in the malignant hyperthermic syndrome have led to concern about the interaction of volatile anesthetics (and other anesthetic agents) with calcium metabolism in the muscle cell. Many of the phenomena caused by anesthetics appear to have common mechanisms in all of the muscle types; however, the differences among skeletal, cardiac and smooth muscle also lead to distinct effects of the anesthetics in each. Given the diverse research disciplines which have been brought to hear on the mechanism of anesthetic alteration of contractility, the symposium from which this book originates was convened for the purpose of gathering those with common interests in anesthetic agents and their cellular and subcellular actio | 出版日期 | Book 1991 | 关键词 | Calcium; depression; hemodynamics; lead; metabolism; research | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4684-5979-1 | isbn_softcover | 978-1-4684-5981-4 | isbn_ebook | 978-1-4684-5979-1Series ISSN 0065-2598 Series E-ISSN 2214-8019 | issn_series | 0065-2598 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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