Titlebook: Mechanisms in Carcinogenesis and Cancer Prevention; Harri U. Vainio,Eino K. Hietanen Book 2003 Springer-Verlag Berlin Heidelberg 2003 angi

Free-Radical

敲竹杠

Detoxification

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0171-2004 g the last 50 years, account for a majority of all cancer deaths. However, still rather little is known, about how environmental and genetic factors interact, how they may regulate gene activation etc. And it is a long way from the discovery of a basic regulatory mechanism to practical patient treat

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Genetic and Environmental Factors in Carcinogenesis,be imprecise and even arbitrary. Even so, an understanding of these causes will be helpful for scientific, clinical, and cancer preventive measures. A certain notion of cancer causation, often implicit, underlies many science and health policy decisions.

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Dedication

Hormonal Carcinogenesis,to divide. Hormones and growth factors have well-documented roles in maintaining a proper balance between cellular differentiation, proliferation, and programmed death (. 1991; . and . 1996). Thus, alterations in the endogenous hormone and growth factor metabolism, or use of exogenous hormones for c

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Arachidonic Acid Pathway in Cancer Prevention,process; AA metabolism is increased during inflammation. The major pathways of AA metabolism, PG synthesis and LT synthesis, are associated strongly with carcinogenesis; both are inhibited by antioxidants and anti-inflammatory agents. Evidence also suggests that direct modulation of cellular AA leve