Titlebook: Mechanisms in B-Cell Neoplasia 1994; Michael Potter (Chief),Fritz Melchers (Director) Book 1995 The Editor(s) (if applicable) and The Auth

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书目名称Mechanisms in B-Cell Neoplasia 1994读者反馈学科排名

替代品

Detection of B-Cells Clonally Related to the Tumor Population in Multiple Myeloma and MGUStumor population, followed by sequence determination of the PCR product. This sequence is clonally unique due to novel combinations of V-D-J gene segments, random nucleotide insertions and deletions, and somatic mutations. Allele specific oligonucleotide (ASO) primers can then be synthesized and used to detect the tumor specific allele [1].

manifestation

肌肉

Induction of Plasmacytomas in Genetically Susceptible Mice with Silicon Gelse silicone gel is degraded over a long period of time. Preliminary studies with long chain liquid dimethylpolysiloxanes with viscosities of 1000 cSt and 12,500 cSt have not produced plasmacytomas as yet. The plasmacytomagenic action of the gel appears to be due to the release of liquids from the gel matrix.

Tailor

Classification of Mouse Lymphomasnerally applicable irrespective of etiology, since thymic lymphomas induced chemically with virus (Joshi and Frei 1970) or occurring in transgenic mice (Pattengale 1994) are morphologically similar. The classification attempts to provide a diagnosis based on morphology supported by molecular and immunologic analysis.

Ondines-curse

The Blood B-Cells and Borie Marrow Plasma Cells in Patients with Multiple Myeloma Share Identical Igells. In all 10 of those patients the same clonotypic rearrangement was amplified from the purified blood B cells. The relationship of these clonal blood B cells to the malignant bone marrow plasma cells remains undetermined

脱落

Alterations of the BCL-6 Gene in Diffuse Large-Cell Lymphoma0). Several molecular alterations have been detected at variable frequency in these tumors, but none has been specifically or consistently associated with the disease (Ladanyi et al. 1991, Offit et al. 1989a).

杀死

B-1 (CD 5+) B-Cells as a Marker of Immune Dysregulation in Multiple Myeloma pokeweed mitogen (PWM). In this system the inhibition of Ig production by added cell populations or culture supernatants is determined. Recently the use of Staphylococcal Aureus protein (SAC) as a stimulant proved a satisfactory system as well.

欢呼

确保

978-3-642-79277-9The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE