书目名称 | Mechanism of Functional Expression of the Molecular Machines |
编辑 | Masahiro Kinoshita |
视频video | |
概述 | Provides many illustrations to facilitate understanding.Gives explanations in words rather than by mathematical equations.Offers detailed descriptions so that readers can understand without referring |
丛书名称 | SpringerBriefs in Molecular Science |
图书封面 |  |
描述 | This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system. |
出版日期 | Book 2016 |
关键词 | ATP hydrolysis cycle; molecular machine; motor protein; self assembly; water entropy; Protein-Ligand Inte |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-10-1486-4 |
isbn_softcover | 978-981-10-1484-0 |
isbn_ebook | 978-981-10-1486-4Series ISSN 2191-5407 Series E-ISSN 2191-5415 |
issn_series | 2191-5407 |
copyright | The Author(s) 2016 |