Titlebook: Maturation Phenomenon in Cerebral Ischemia II; Neuronal Recovery an Umeo Ito,Takaaki Kirino,Igor Klatzo (Former Chief Conference proceedin

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Neuroprotection by Drug-Induced Neurotrophic Factorsl/glial hippocampal cultures to clenbuterol (1–100.) and selegiline (10p.-1.) significantly enhanced the content of NGF measured in the culture medium by two-site enzyme linked immunosorbent assay (ELISA). The excitotoxic injury was induced in the same type of cells after 14 days in vitro by exposur

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Stress Response and Ischemic Tolerance in the Brainunder the stress of H—R. Another unique stress protein, oxygen-regulated protein 150 (ORP150), was purified and through several experimental steps we cloned the ORP150 gene successfully. These stress proteins may contribute to the adaptive response of astrocytes to ischemic stress, thereby ultimatel

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Preconditioning Depresses Excitatory Cell Signaling Following the Second Ischemic Insults are markedly diminished after 24h of recovery. We propose that during the preconditioning, protective factors (growth factors and cytokines) are induced in neurons and/or glia cells, which in turn stimulate intracellular neuroprotective mechanisms such as enhancers of proteins synthesis or bcl-2 e

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