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Titlebook: Matrix Metalloproteinases in Tissue Remodelling and Inflammation; Vincent Lagente,Elisabeth Boichot Book 2008 Birkhäuser Basel 2008 Activa

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书目名称Matrix Metalloproteinases in Tissue Remodelling and Inflammation
编辑Vincent Lagente,Elisabeth Boichot
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概述Provides new advances regarding the involvement of MMPs in inflammatory diseases.Written by leading experts in the field.International authorship
丛书名称Progress in Inflammation Research
图书封面Titlebook: Matrix Metalloproteinases in Tissue Remodelling and Inflammation;  Vincent Lagente,Elisabeth Boichot Book 2008 Birkhäuser Basel 2008 Activa
描述.Matrix metalloproteinases (MMPs) are proteolytic enzymes believed to be involved in many physiological and pathological processes associated with inflammatory reactions. MMP synthesis and functions are regulated by three major mechanisms including transcriptional activation, post-transcriptional processing, and control of activity by tissue inhibitors of metalloproteinases (TIMPs). Many cell types have been identified as producers of MMPs and TIMPs in a context of inflammatory processes. MMPs are involved in numerous inflammatory diseases, including respiratory, cardiovascular and central nervous system pathologies...This volume presents new advances in the involvement of MMPs in various diseases associated with inflammatory processes. Moreover, the recent development of selective and non selective inhibitors of MMPs provides new insights in the relationship between activation of inflammatory cells and tissue remodelling and advises new therapeutic possibilities for the treatment of inflammatory diseases..
出版日期Book 2008
关键词Activation; Atmen; Tissue Remodelling; asthma; cell; development; diseases; enzyme; enzymes; inflammation; pat
版次1
doihttps://doi.org/10.1007/978-3-7643-8585-9
isbn_ebook978-3-7643-8585-9Series ISSN 1422-7746 Series E-ISSN 2296-4525
issn_series 1422-7746
copyrightBirkhäuser Basel 2008
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Role of matrix metalloproteases in pulmonary fibrosis,es, drugs, and radiation. Independent of etiology, the fibrotic response in the lung can be visualized as a dynamic and highly integrated cellular response to persistent injury and may be related to a damage-triggered inflammatory response or to an aberrant epithelial or endothelial reaction. In any
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Anti-inflammatory properties of MMP inhibitors in experimental models of chronic obstructive pulmont in the process of lung disease associated with tissue remodelling. Furthermore, the concept that modulation of airway remodelling including excessive proteolysis damage of the tissue, may be of interest as a basis for future treatment. Among the metalloproteinases (MMPs) family, macrophage elastas
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