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Titlebook: Mathematical and Statistical Modeling for Emerging and Re-emerging Infectious Diseases; Gerardo Chowell,James M. Hyman Book 2016 Springer

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Optimal Control of Vaccination in an Age-Structured Cholera Model,nique optimal control are derived. The steps to justify the optimal control results for such a system with first order PDEs are given. Numerical results illustrate the effect of age structure on optimal vaccination rates.
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Statistical Considerations in Infectious Disease Randomized Controlled Trials,are covered. Some challenges with sample size determination are outlined and updated methods for data monitoring, interim, and subgroup analyses detailed. Also, discernment is made between multisite and cluster randomized trials. Recommendations for best practices are included.
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Modeling the Impact of Behavior Change on the Spread of Ebola,acilities. We found that reducing the number of contacts made by infectious individuals in the general population is the most effective intervention method for mitigating an EVD epidemic. While healthcare interventions delayed the onset of the epidemic, healthcare alone is insufficient to stop the epidemic in the model.
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Evaluating the Number of Sickbeds During Ebola Epidemics Using Optimal Control Theory, development of the Ebola epidemic in West Africa was the lack of public health surveillance systems to detect new outbreaks and the healthcare capacity that is needed to enforce infection control practices.
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Patch Models of EVD Transmission Dynamics,onfidence intervals as functions of the number of data points used to calibrate the models. The patch models show an improvement over the logistic model in short-term forecasting, but naturally require the estimation of more parameters from limited data.
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Book 2016 aspects of an emerging epidemic.Readers will discover a broad range of approaches to address questions, such as.Can we control Ebola via ring vaccination strategies?.How quickly should we detect Ebola cases to ensure epidemic control?. What is the likelihood that an Ebola epidemic in West Africa le
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