书目名称 | Mathematical Grammar of Biology |
编辑 | Michel Eduardo Beleza Yamagishi |
视频video | |
概述 | Offers the first detailed development of the conceptual theoretical framework necessary to search for DNA’s first principles.Shows how mathematical modeling can be applied to the study of DNA’s langua |
丛书名称 | SpringerBriefs in Mathematics |
图书封面 |  |
描述 | .This seminal, multidisciplinary book shows how mathematics can be used to study the first principles of DNA. Most importantly, it enriches the so-called “Chargaff’s grammar of biology” by providing the conceptual theoretical framework necessary to generalize Chargaff’s rules. Starting with a simple example of DNA mathematical modeling where human nucleotide frequencies are associated to the Fibonacci sequence and the Golden Ratio through an optimization problem, its breakthrough is showing that the reverse, complement and reverse-complement operators defined over oligonucleotides induce a natural set partition of DNA words of fixed-size. These equivalence classes, when organized into a matrix form, reveal hidden patterns within the DNA sequence of every living organism. Intended for undergraduate and graduate students both in mathematics and in life sciences, it is also a valuable resource for researchers interested in studying invariant genomic properties.. |
出版日期 | Book 2017 |
关键词 | Mathematical DNA rules; Intrinsic properties of DNA; Bioinformatics; Genomics; Symmetry Principle; Charga |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-62689-5 |
isbn_softcover | 978-3-319-62688-8 |
isbn_ebook | 978-3-319-62689-5Series ISSN 2191-8198 Series E-ISSN 2191-8201 |
issn_series | 2191-8198 |
copyright | The Editor(s) (if applicable) and The Author(s) 2017 |