Titlebook: Mass Spectrometry Imaging of Small Molecules; Lin He Book 2015 Springer Science+Business Media New York 2015 MALDI-MS.biological metabolom

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Laser Ablation Sample Transfer for Mass Spectrometry Imaging,solution is approximately 400 μm and limited by the spread of the laser desorption plume. IR-LAST for MALDI imaging provides several new capabilities including ambient sampling, area to spot concentration of ablated material, multiple ablation and analysis from a single section, and direct deposition on matrix-free nanostructured targets.

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Laser Desorption Postionization Mass Spectrometry Imaging of Biological Targets,cial instruments. For this reason, a generalized protocol is presented here for the use of LDPI-MS imaging to detect small molecules within intact biological samples. Examples are provided here for LDPI-MS imaging of an antibiotic within a tooth root canal and a metabolite within a coculture bacterial biofilm.

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Book 2015nd new methodological approaches. Chapters provide detailed operational instructions from sample preparation to method selection, from comparative quantification to structural identification and from data collection to visualization of small molecule mapping in complex samples. Written in the highly

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