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Titlebook: Marginal Models; For Dependent, Clust Jacques A.‘Hagenaars,Marcel A. Croon,Wicher Bergsm Book 2009 Springer-Verlag New York 2009 Fitting.In

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Wicher Bergsma,Marcel Croon,Jacques A. Hagenaarsomatin domains are located in the nuclear interior, whereas silent domains reside at the nuclear periphery. Global changes in gene expression correlate with spatial chromatin reorganizations that play a significant role during development. Thus, transcriptionally active genes are involved in the pro
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Wicher Bergsma,Marcel Croon,Jacques A. Hagenaars, being used as a structural backbone of ribosomes (ribosomal RNA (rRNAs)), adaptor molecules in protein translation (transfer RNA (tRNAs)) and regulators of mRNA stability, protein translation and chromatin density (long ncRNAs and micro RNAs (miRNAs), for more details see Sect. 13.2). A gene is co
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Wicher Bergsma,Marcel Croon,Jacques A. Hagenaarsexpression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. Th is pivotal role for the regulation of gene expression makes this textboo
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Wicher Bergsma,Marcel Croon,Jacques A. Hagenaarsme is composed of some 20,000 protein-coding genes and an even higher number of genes for non-coding RNAs (ncRNAs) as well as a large number of pseudogenes. An essential condition that a gene can be expressed, ., transcribed into RNA, is that it its regulatory regions, such as transcription start si
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2199-7357 iew of the basic principles of marginal modeling and offers a wide range of possible applications. Marginal models are often the best choice for answering important research questions when dependent observations are involved, as the many real world examples in this book show...In the social, behavio
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