Titlebook: Managing Metastatic Prostate Cancer In Your Urological Oncology Practice; K.C Balaji Book 2016 Springer International Publishing Switzerla

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,Cancer Vaccines in Castration Resistant Prostate Cancer—An Evolution in Design,udying immunotherapy in prostate cancer, the current immunologic modalities under development, and how to develop novel immune strategies either alone or in combination with other agents remains a challenge that may yet to be solved as more biologic agents become available for testing. Understanding

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,Sequencing Therapies in Metastatic Castration—Resistant Prostate Cancer,leucel-t and radium-233) should be utilized. In this chapter, we will discuss the key issues surrounding the decision-making that goes into choosing one CRPC drug over another; review the biologic basis for cross-resistance between agents; and highlight some of the data in support of clinical cross-

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Novel Therapies in Castration-Resistant Prostate Cancer,allow for more specific delivery of drug to cancer cells in hopes of improving efficacy while decreasing systemic toxicity. Targeting stemness pathways such as Hedgehog and Notch signaling may provide a way to block self-renewing stem-like cells. Treatment with antisense oligonucleotides may be used

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the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and will include the most up to date scientific and clinical information..978-3-319-52457-3978-3-319-31341-2

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