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Titlebook: Management of Neuroendocrine Tumors of the Pancreas and Digestive Tract; From Surgery to Targ Eric Raymond,Sandrine Faivre,Philippe Rusznie

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发表于 2025-3-21 16:41:39 | 显示全部楼层 |阅读模式
书目名称Management of Neuroendocrine Tumors of the Pancreas and Digestive Tract
副标题From Surgery to Targ
编辑Eric Raymond,Sandrine Faivre,Philippe Ruszniewski
视频video
概述The latest advances in the management of neuroendocrine tumors.Multimodal approaches used for the treatment of neuroendocrine tumors of the gut.Top international experts in the field.Due to the rarity
图书封面Titlebook: Management of Neuroendocrine Tumors of the Pancreas and Digestive Tract; From Surgery to Targ Eric Raymond,Sandrine Faivre,Philippe Rusznie
描述.This book pursues a multidisciplinary approach, presenting chapters with updated information on various aspects of treatment for patients with neuroendocrine tumors. Authors have been selected from expert centers in Europe and the United States. The goal of this book is to comprehensively summarize recent data and provide inspiring ideas to optimize the care of patients with neuroendocrine tumors..Neuroendocrine tumors are fascinating multifaceted diseases that can primarily localize in many organs with various presentations. These tumors are rare but their increasing incidence renders likely that physicians caring for cancers may have either already faced or may be certainly exposed to diagnose and/or treat a patient with neuroendocrine tumors. Over the last years, novel therapeutic options have emerged for neuroendocrine tumors, profoundly challenging practices that had previously been the standards for decades. These include - but are not limited to - somatostatin analogues, targeted therapies such as tyrosine kinase and mTOR inhibitors, antiangiogenic compounds, but also peptide-receptor targeted therapy or radioembolization. This changing field has generated novel treatment a
出版日期Book 2014
关键词Angiogenesis; Carcinoid; Pancreatic neuroendocrine tumors; Somatostatin receptors; Tyrosine kinase inhib
版次1
doihttps://doi.org/10.1007/978-2-8178-0430-9
isbn_softcover978-2-8178-0554-2
isbn_ebook978-2-8178-0430-9
copyrightSpringer-Verlag France 2014
The information of publication is updating

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Advances with Somatostatin Analogs in Neuroendocrine Tumors; The Promise of Radionuclides in Neuroend dual-targeting chimeric molecules. Conjugation of SST analogs with radionuclides has also been used for peptide-receptor-targeted radiotherapy (PRRT) in advanced NETs, with promising results. This chapter summarizes key preclinical and clinical data on the antisecretory and antitumor effects of S
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Streptozocin-Based Chemotherapy: Still a Standard of Care for Neuroendocrine Tumours?, therapies and this may be important in those who are symptomatic from tumour burden and those with locally advanced disease who may be down-staged for resection. The role of Ki67 and other predictive markers requires further assessment in prospective studies as does the relative efficacy of alterna
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Angiogenesis Inhibition Using Sunitinib in Pancreatic Neuroendocrine Tumors, trial. In this later study, sunitinib demonstrated significant benefits in terms of progression-free survival and response rate in patients with advanced well-differentiated pancreatic neuroendocrine tumors. The safety profile in this patient population was consistent with previously reported data
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Clinical Management of Targeted Therapies in Neuroendocrine Tumours,ons, and providing strategies to overcome them is a further important component of patient care. At the core of clinical management is effective communication between patients and physicians, which ensures patients are fully involved in decisions concerning their care, and will allow advances in the
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Imaging of Neuroendocrine Tumors and Challenges in Response Evaluation for Targeted Therapies,ving targeted agents. In this chapter, we aimed to review the various imaging techniques used to characterize neuroendocrine tumors in routine clinic and clinical trials. We also challenge the potential advantages of those imaging techniques for the evaluation of response in patients with neuroendoc
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Overcoming Resistance to Targeted Therapies: The Next Challenge in Pancreatic Neuroendocrine Tumorsesponse) resistance to antiangiogenic agents and mTOR inhibitors, using data available from preclinical and clinical studies in various malignancies. Herein, we also describe how these general mechanisms of resistance may emerge in patients with PNET treated with sunitinib and everolimus. Overcoming
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