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Titlebook: Management of Hematological Cancer in Older People; Ulrich Wedding,Riccardo A. Audisio Book 2015 Springer-Verlag London 2015 Geriatric.Ger

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Myelodysplastic Syndromes in Older Patients,cterized by a dysplastic hematopoiesis and cytopenias in the peripheral blood. Clinical manifestations of MDS are variable and range from mild symptoms related to anemia, thrombocytopenia or granulocytopenia to the transformation to acute myeloid leukemia. The availability of promising treatment opt
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Acute Myeloid Leukemia,t outcomes than younger patients. Selected older patients can benefit from curative therapies, but as a group they experience increased treatment-related toxicity, are more likely to relapse, and have decreased overall survival. Age-related outcome disparity is in part explained by differences in tu
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Chronic Myelogeneous Leukemia,osed with CML in chronic phase had shorter survival compared to younger patients. With the advent of targeted therapy with imatinib, studies described consistently improved responses in elderly late chronic phase patients treated with imatinib after IFN failure, with similar overall survival compare
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Hodgkin Lymphoma in the Elderly,p affected with this disease. The reasons for this are multifactorial, and in part due to the presence of co-morbid illness, the inability to tolerate therapies which are curative in younger age cohorts, poor functional status and intrinsic biological disease characteristics which differ between the
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