| 书目名称 | Management of Breast Cancer in Older Women | | 编辑 | Malcolm W. Reed,Riccardo A. Audisio | | 视频video | | | 概述 | The proposed contributors to this text represent the leading opinions in their relevant fields. This will ensure the credibility of this text with the proposed readership..The text covers all aspects | | 图书封面 |  | | 描述 | I was looking at Mrs T – all 45 kilos of her – with somewhat puzzled thoughts. I had prescribed her capecitabine at very prudent doses, in view of her 91-year-old kidneys and physiology. She had reduced my treatment even further, “because it was making her tired.” As a result, she was taking a grand total of 500 mg of capecitabine a day. Yet, her metastatic, ER/PR-negative, Her2-positive breast cancer was undoubtedly responding. Her pain was improving and her chest mass was shrinking, as were her lung metastases… What was the secret of that response? Were Mrs T’s kidneys eli- nating even less drug than predicted by her creatinine clearance? Was her sarcopenia altering drug distribution? Was she absorbing more drug than average? Or was her tumor exquisitely sensitive to fluoropyrimidines? “Physicians,” said Voltaire, “pour drugs they know little for diseases they know even less into patients they know no- ing about.” Medicine has made tremendous progress since the eighteenth century. Yet, there are fields where quite a lot remains to be learned. In developed countries, 25% of breast cancers occur in patients aged 75 years and older. Yet, these patients represent only 4% of the popul | | 出版日期 | Book 20101st edition | | 关键词 | Tumor; aging; assessment; cancer; geriatrics; Diagnostic Radiology; surgical oncology | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-84800-265-4 | | isbn_ebook | 978-1-84800-265-4 | | copyright | Springer-Verlag London Limited 2010 |
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发表于 2025-3-21 19:30:02
