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Titlebook: Mammalian Transient Receptor Potential (TRP) Cation Channels; Volume I Bernd Nilius,Veit Flockerzi Book 2014 Springer-Verlag Berlin Heidelb

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https://doi.org/10.1007/978-3-642-54215-2Pain perception; TRP channels; TRP pharmacology; Temperature sensors
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Bernd Nilius,Veit FlockerziGives an excellent overview on mammalian TRP cation channels, a rapidly moving field.Written by outstanding authorities in the field.With numerous illustrations
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Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/m/image/622045.jpg
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TRPs: Truly Remarkable Proteins,involved in a plethora of cell functions and have been identified as causal for many hereditary and acquired diseases. We shortly introduce these channels, summarize nomenclature and chromosomal location of the 28 mammalian . genes, and list the available .-deficient mouse lines.
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The TRPV4 Channelus, plant-derived, and synthetic ligands) stimuli. In this chapter we will review TRPV4 expression, biophysics, structure, regulation, and interacting partners as well as physiological and pathological insights obtained in TRPV4 animal models and human genetic studies.
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Book 2014eceptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
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TRPV2PV2 is high in some types of cells including neurons, neuroendocrine cells, immune cells involved in innate immunity, and certain types of cancer cells. TRPV2 may modulate various cellular functions in these cells.
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