Titlebook: Male Hypogonadism; Basic, Clinical, and Stephen J. Winters (Chief) Book 20041st edition Springer Science+Business Media New York 2004 Gonad

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Stephen J. Winters (Chief)Includes supplementary material:

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Contemporary Endocrinologyhttp://image.papertrans.cn/m/image/621917.jpg

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Neuroendocrine Control of Testicular Function,r hypothalamus. When it reaches the anterior pituitary, GnRH stimulates the synthesis and secretion of the pituitary gonadotropic hormones, luteinizing hormone (LH), and follicle-stimulating hormone (FSH). LH and FSH are released into the circulation in bursts and activate G protein-coupled receptor

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Leydig Cell Function in Man,ferentiation, gamete production and maturation, and development of secondary sexual characteristics. In this chapter, the development, steroidogenic function, and regulation of human Leydig cells are summarized. Clinical aspects of androgen secretion and pathology related to Leydig cells are also re

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Male Hypogonadism Resulting From Mutations in the Genes for the Gonadotropin Subunits and Their Recsing mutations, the emerging knowledge about single nucleotide and microsatellite polymorphisms in the human genome is adding a new level of complexity to genomic function, providing the structural basis for individual variability of the genome and its phenotypic expression. All mutations can, in pr

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Male Hypogonadism Resulting From Disorders of the Pituitary and Suprasellar Region,ortal vascular system. GnRH stimulates the synthesis and secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are produced by gonadotrophs of the anterior pituitary. LH stimulates testosterone synthesis after binding to specific receptors on Leydig cells, whereas Serto

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,Klinefelter’s Syndrome,is also the most common cause of primary testicular failure, resulting in impairments in both spermatogenesis and testosterone production. The hypogonadism associated with KS can range from mild to severe, leading to a marked variation in clinical presentation. Men with KS possess at least one addit