Titlebook: Male Breast Cancer; Ian Fentiman Book 2017 Springer International Publishing Switzerland 2017 Breast cancer.Surgery.Oncology.Genetics.MBC.

CHOP

Genetics,le in MBC whereas those of . may be associated with up to 14% of male cases. Mutations of ., partner and localiser of BRCA2, have been found in 16% of MBC cases, with or without a family history. In a large genome wide association study a common variant of . a low penetrance gene, was found to be si

Conquest

Histopathology,ransform this into accurate prognostic data. Invasive ductal carcinoma predominates with variants of papillary and secretory carcinoma occurring more proportionally more frequently in MBC than FBC. Pure mucinous carcinomas are associated with a good prognosis whereas micropapillary invasive cancers

Neuropeptides

Molecular Profile,pared with approximately 70% of FBC. Androgen receptor mutations may be responsible for occasional MBC cases but for the majority no clear link has been shown. MIB1 is not of prognostic significance in MBC, nor is bcl2 expression. The molecular subtypes of MBC are predominantly luminal A, sometimes

含糊其辞

野蛮

Surgery,can be treated by breast conserving surgery (BCS), that is, nipple conserving surgery for MBC. In the absence of controlled randomised trials, large databases such as SEER have been analysed and results suggest similar cancer specific survival in males treated with lumpectomy and radiotherapy compar

减弱不好

Lipoprotein(A)

记忆法

OREX

Plaque