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Titlebook: Macromolecular Protein Complexes; Structure and Functi J. Robin Harris,Jon Marles-Wright Book 2017 Springer International Publishing Switze

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楼主: ARRAY
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Symmetry-Directed Design of Protein Cages and Protein Lattices and Their Applications,al cages or extended lattices that are characterized by a high degree of symmetry; examples include viral capsids and bacterial S-layers. The precisely defined higher order structure exhibited by these assemblies has inspired efforts to design such structures . by applying the principles of symmetry
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Structure and Function of RNA Polymerases and the Transcription Machineries,ate for protein synthesis during translation. In bacteria, archaea and eukaryotes, transcription is carried out by multi-subunit RNA polymerases (RNAPs) sharing a conserved architecture of the RNAP core. RNAPs catalyse the highly accurate polymerisation of RNA from NTP building blocks, utilising DNA
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Dihydrodipicolinate Synthase: Structure, Dynamics, Function, and Evolution,osynthesis and focus on the enzyme dihydrodipicolinate synthase in terms of its structure, function and the evolution of its varied number of subunits (quaternary structure). Dihydrodipicolinate synthase is the first committed step in the biosynthesis of lysine, which occurs naturally in plants, bac
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,“Pyruvate Carboxylase, Structure and Function”,ep of gluconeogenesis. This large enzyme is multifunctional, and each subunit contains two active sites that catalyze two consecutive reactions that lead to the carboxylation of pyruvate into oxaloacetate, and a binding site for acetyl-CoA, an allosteric regulator of the enzyme. Pyruvate carboxylase
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The Ccr4-Not Complex: Architecture and Structural Insights,different roles that impact eukaryotic gene expression. It has a conserved core of three Not proteins, the Ccr4 protein, and two Ccr4 associated factors, Caf1 and Caf40. A fourth Not protein, Not4, is conserved, but is only a stable subunit of the complex in yeast. Certain subunits have been duplica
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Protein Complexes in the Nucleus: The Control of Chromosome Segregation, lethal to the cells and cause spontaneous miscarriages. However, in some cases, defects in the spindle assembly checkpoint lead to severe diseases, such as cancer and birth and development defects, including Down’s syndrome. The timely and accurate control of chromosome segregation in mitosis relie
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