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Titlebook: Macrolide Antibiotics; Wolfgang Schönfeld,Herbert A. Kirst Book 2002 Springer Basel AG 2002 Antibiotika.Infektionskrankheiten.Sexually Tra

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Activity of macrolides against mycobacteria, proportion of all serious infectious disorders observed worldwide. Estimates of the numbers of leprosy cases exceed 20 million. Tuberculosis in all of its forms is believed to be the most common of the fatal infections, with total annual mortality figures of three million adult deaths of adults in
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, and asthma and atherosclerosis: role of macrolides,tracellular parasites that have a unique developmental cycle with morphologically distinct infectious and reproductive forms. All members of the genus have a gram-negative envelope without peptidoglycan, share a genus-specific lipopolysaccharide (LPS) antigen, and utilize host ATP for the synthesis
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Activity of macrolides in sexually transmitted diseases,led with the established safety profile of erythromycin and the advent of newer compounds with improved pharmacokinetic and pharmacodynamic profiles of particular relevance to bacterial sexually transmitted diseases (STDs), has resulted in a recent surge of interest in their clinical use.
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Effects of macrolide antibiotics on ribosome function,n composition of this organelle, a disproportionately large number of structurally diverse agents target the ribosome. The ribosome catalyzes polymerization of amino acids in the sequence dictated by the nucleotide sequence in mRNA. The process of protein biosynthesis requires a spatial and temporal
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