| 书目名称 | MIPs and Their Roles in the Exchange of Metalloids |
| 编辑 | Thomas P. Jahn,Gerd P. Bienert |
| 视频video | |
| 概述 | Dedicated to the metalloids, a recently discovered group of substrates for a number of specific MIPs in a diverse spectrum of organisms.Aspects of the environmental chemistry of metalloids relevant to |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | Sixteen years have passed since human aquaporin-1 (AQP1) was discovered as the first water channel, facilitating trans-membrane water fluxes. Subsequent years of research showed that the water channel AQP1 was only the tip of an iceberg; the iceberg itself being the ubiquitous super family of membrane intrinsic proteins (MIPs) that facilitate trans-membrane transport of water and an increasing number of small, water-soluble and uncharged compounds. Here we introduce you to the superfamily of MIPs and provide a summary about our gradually refined understanding of the phylogenetic relationship of its members. This volume is dedicated to the metalloids, a recently discovered group of substrates for a number of specific MIPs in a diverse spectrum of organisms. Particular focus is given to the essential boron, the beneficial silicon and the highly toxic arsenic. The respective MIP isoforms that facilitate the transport of these metalloids include members from several clades of the phylogenetic tree, suggesting that metalloid transport is an ancient function within this family of channel proteins. Among all the various substrates that have been shown to be transported by MIPs, metalloids |
| 出版日期 | Book 2010 |
| 关键词 | Bienert; Exchange; Jahn; MIP; Metalloids; environment; protein; proteins; protozoa; toxicity |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4419-6315-4 |
| isbn_softcover | 978-1-4939-4100-1 |
| isbn_ebook | 978-1-4419-6315-4Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
发表于 2025-3-21 19:22:43
