书目名称 | MAP Kinase Signaling Protocols | 编辑 | Rony Seger | 视频video | | 概述 | Presents easy-to-use, comprehensive, and fully updated techniques to study MAPKs.Serves a wide variety of scientists, from cellular biologists and biochemists to disease specialists seeking cures to d | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | Mitogen-activated protein (MAP) kinase (MAPK) cascades are key signaling components that govern essentially all cellular processes evoked by any type of stimulation, and it has been well established that the malfunctioning of these cascades leads to various diseases including cancer, autoimmunity, and diabetes.In MAP Kinase Signaling Protocols, Second Edition, expert researchers fully update the popular first edition the key techniques used in the study of MAPK signaling cascades in various cellular contexts.This thorough volume explores essential topics such as activation and function of components of theMAPK signaling cascades, the study of MAPK cascades as transmitters of membranal receptor signals, structure-function relationships of MAPKs, studies on the regulation of MAPK cascades, the use of lower organisms, animal models, and human genetics in the study of MAPKs, as well as the study of MAPKs in specific systems and diseases.Written in the highly successful Methods in Molecular Biology™ series format, chapters includes introductions to their respective subjects, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troublesho | 出版日期 | Book 2010Latest edition | 关键词 | Activation; Cancer and inflammation; Cell signaling; Endoplasmatisches Reticulum; Enzymatic activity; Gro | 版次 | 2 | doi | https://doi.org/10.1007/978-1-60761-795-2 | isbn_softcover | 978-1-4939-6105-4 | isbn_ebook | 978-1-60761-795-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC 2010 |
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