Titlebook: MAP Kinase Signaling Protocols; Rony Seger Book 20041st edition Humana Press 2004

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1064-3745 al role in the intracellular transmission of extracellular signals. These cascades operate as major lines of communication within a complicated signaling network that regulates many cellular processes, including proliferation, differentiation, development, stress response, and apoptosis. More than 1

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Activation of SAPKs/JNKs and p38s In Vitro,al, the same stimuli that activate the SAPKs/JNKs will also activate the p38s. One exception is ischemia-reperfusion. In this instance, the SAPKs/JNKs are activated exclusively during reperfusion, while the p38s are activated during ischemia and remain active during reperfusion (.).