Titlebook: Lynch Syndrome; Molecular Mechanism Naohiro Tomita Book 2020 Springer Nature Singapore Pte Ltd. 2020 Colorectal cancer.Colorectal neoplasm

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Screening for Lynch Syndrome,as clinical screening testing using family history and cancer history. Since these screening testings do not detect all colorectal cancer with microsatellite instability, the universal tumor screening for Lynch syndrome using microsatellite instability testing or immunohistochemistry of mismatch rep

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Surveillance Colonoscopy for Lynch Syndrome Affected Individuals,ous colorectal cancer in the residual colon and/or rectum after surgery. The same responsibility applies to another Lynch syndrome-associated cancer, ex gastric cancer, and duodenal cancer, and also to surveillance of the relatives who have the same pathogenic variant of Lynch syndrome proband. In t

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Surgical Approach for Colorectal Cancer in Patients with Lynch Syndrome,cancer (CRC) is a hallmark of the syndrome, and the cumulative risk of CRC ranges from 10 to 46% by 70 years old, depending on the gene affected. Moreover, despite the high cumulative risk of subsequent CRC (metachronous CRC) after the first CRC is managed with surgery, the optimal surgical treatmen

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Chemoprevention for Lynch Syndrome-Associated Malignancies,y thought. The development of next-generation sequencing gene panel testing will diagnose more patients; thus, the number of Lynch syndrome (LS) patients may increase in the future. As a result, we must perform CRC screening and target preventive measures to younger individuals. In addition to diet

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International Collaboration for Lynch Syndrome, due to the insignificant manifestation of the disease compared to other hereditary CRCs such as FAP, which typically develops thousands of polyps in a large intestine and simply identified by colonoscopy. International collaboration is always essential in understanding of the etiology and the clini

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Kazuo Tamuraformation from the manufacturing industry.Proposes a leaders.This book presents a novel approach for studying the impact of leadership styles on supply chain resilience using a combination of transactional and transformational leadership. The book consists of two main sections: The first introduces

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acquisition

Harumi Saeki,Okio Hinornal and external customers (Krajewski et al. 2016, .. 11th ed. Pearson Education Limited; Moscoso and Lago 2017, .. McGraw Hill Education). The transformation of inputs into outputs in terms of products and services requires the intervention of human beings, and the effective coordination of the hu

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Shigeki SekineHendijani, .(3), 12–30, 2019; Moscoso and Lago, ., McGraw Hill Education, 2017; Donohue et al., .(1), 191–202, 2020). It emphasises the significant role human beings play in operations management. Amongst all the inputs required for any operations architecture, the human being is the only one that c