Titlebook: Lymphatic Tissue and Germinal Centers in Immune Response; Proceedings of the S L. Fiore-Donati,M. G. Hanna Conference proceedings 1969 The

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The Development of Lymphoid Systems: Immune Response and Radiation Sensitivity in Lower Vertebratescells show considerably greater resistance to destructive effects both of ionizing irradiation and of certain alkylating agents [3, 4, 5, 6, 7]. Among the cells known to be highly susceptible to irradiation are mammalian small lymphocytes, including lymphocytes residing within the thymus.

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The White Pulp of the Human Spleen in Three Dimensions, and its Relation to Immunologic Functions the ovarian follicle, anatomic changes may accompany changes in function, but the cells involved are stationary; germinal center cells, however, are migratory. It is not known whether any cells migrate into the centers from the outside, but the numerous mitotic figures give ample evidence that the

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Differentiation Pathway within Germinal Centers of Human Tonsilsady-state immune response. The presence of large germinal centers and numerous plasma cells within these structures indicates that the lymphoreticular tissue at this site is involved in the production of humoral antibodies. It has been recognized that tonsillar germinal centers show a distinct polar

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Histophysiology of Germinal Centers and their Role in Antibody Response: An Autoradiographic Study iagainst an antigen, leading to the production of humoral antibodies, is still a matter of discussion. Experiments as done by Nossal and co-workers [1] have shown that at least part of the antigen is trapped in some way or another within the germinal center. Hanna [2] has shown that germinal center c

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