Titlebook: Lymph Node Metastasis in Gastrointestinal Cancer; Shoji Natsugoe Book 2019 Springer Nature Singapore Pte Ltd. 2019 Sentinel node navigatio

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Nonclinical Imaging Studies for the Diagnosis of Lymph Node Metastaseshis research field is very important because these tests can yield reliable results at the sacrifice of minimal number of animals..Animal models and imaging modalities must be carefully selected to obtain fruitful results. Recently, imaging devices dedicated for small animal tests have been develope

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Imaging of Lymphatic Vessels and Lymph Nodesuding lymphedema and cancer metastasis. Cancers are complex diseases, and the cancer microenvironment, including lymphatic vessels and blood vessels, play important roles throughout cancer development, from carcinogenesis to malignancy. Efforts aimed at elucidating the pathology of complex cancers a

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Basic Aspect: Methodologylial markers, and the prognostic significance of LNMs has been a major focus for many years. In addition, recent technological innovations have enabled us to detect LNMs more accurately, with some techniques even showing promising applications in the clinical setting. In this chapter, we will review

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Clinical Aspects: Colorectal Cancertage III patients, but not for those who are node-negative, with stage II disease. However, a systematic meta-analysis revealed that the presence of micrometastases in regional lymph nodes (LNs) was associated with poor survival in 4087 patients with node-negative CRC. Unfortunately, the majority of

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Esophageal Cancerristics comparing to gastric or colorectal cancer, and the lymph node dissection during esophageal cancer surgery has more important meaning than that of other gastrointestinal cancer surgeries. The frequency of lymph node metastasis in esophageal cancer is higher than any other gastrointestinal mal

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Gastric Cancerse classification have been harmonized in terms of the N-category determined with the number of metastatic lymph nodes and of the stage grouping..The D-number to describe the extent of lymph node dissection in gastrectomy is used to be defined in accordance with lymph node groups based on the primar

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Colorectal Cancererable research in this field is still being conducted today. If lesions are removed with too wide margins, unnecessary complications can occur with no additional survival benefit. In contrast, incomplete lymph node dissection might leave residual cancer cells, which could cause disease recurrence i