书目名称 | Lupus | 副标题 | Molecular and Cellul | 编辑 | Gary M. Kammer,George C. Tsokos | 视频video | | 丛书名称 | Contemporary Immunology | 图书封面 |  | 描述 | Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages/monocytes, and endothelial cells.Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment. | 出版日期 | Book 1999 | 关键词 | Antigen; apoptosis; autoimmunity; bacteria; cytokine; genetics; inflammation; lymphocytes; macrophages; patho | 版次 | 1 | doi | https://doi.org/10.1007/978-1-59259-703-1 | isbn_softcover | 978-1-4757-5686-9 | isbn_ebook | 978-1-59259-703-1 | copyright | Springer Science+Business Media New York 1999 |
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