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Titlebook: Local Therapies for Glioma; Present Status and F M. Westphal,J.-C. Tonn,Z. Ram Conference proceedings 2003 Springer-Verlag Wien 2003 Surger

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Implantable drug-releasing biodegradable microspheres for local treatment of brain glioma,he development, preclinical studies and clinical trials involving 5-fluorouracil-releasing microspheres for interstitial radiosensitization of malignant glioma. Future developments concerning these microspheres for treatment of brain tumors are presented.
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Non-invasive transcranial High Intensity Focused Ultrasound (HIFUS) under MRI thermometry and guidahin the bore of a 1.5 T MRI scanner (a) to thermally ablate brain lesions such as metastases, (b) to cause precise ablative brain lesions in functional disorders, or (c) to locally open the blood-brain-barrier for targeted therapeutic construct delivery - without the radiation risks of stereotactic
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Intracavitary Treatment of Malignant Gliomas: Radioimmunotherapy Targeting Fibronectin,], with high-grade glioma representing more than 40% of these tumours. Of the high-grade gliomas, gliobastoma multiforme (GBM) is the most prevalent and one of the most aggressive tumours, being highly infiltrative, with tumour cells typically extending several centimetres away from the tumour mass
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Comparing monoclonal antibodies and small peptidic hormones for local targeting of malignant glioma. Since these brain-intrinsic neoplasms are characterized by relentless tumor cell infiltration of normal brain parenchyma, targeting agents require diffusive properties in order to reach invading tumor cell clusters that migrate along vascular clefts and axonal pathways. Tumor uptake was significan
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Gene therapy of gliomas,l recently, our knowledge has mainly been based on chromosomal and molecular studies performed in the last two decades. This has increased tremendously with the advent of new technologies, in particular expression arrays for simultaneous analysis of thousands of genes. Consequently, gene therapy of
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