Titlebook: Liver and Environmental Xenobiotics; S. V. S. Rana,K. Taketa Book 1997 Springer-Verlag Berlin Heidelberg 1997 Stress.drug.liver.metabolism

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Unsaturated-Fat

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Liver Injury and Serum Hyaluronan,trix. The major biological roles of HA include the maintenance of water and protein homeostasis as well as the protection of cells from potentially harmful effects. In the liver, most HA is produced by Ito cells (fat-storing cells, lipocytes, stellate cells) located in the Disse’s spaces [1]. On the

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Phthalic Acid Esters and Liver,de (PVC) plastics used in packaging, storage and delivery of food, drugs and cosmetics. Some of the PAEs are also used as the vehicle for perfumes. A finished plastic product may contain as much as 50% of the plasticizer by weight. Since these plasticizers are not polymerized to the plastic matrix,

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Role of Nitric Oxide (NO) in the D-Galactosamine-Induced Liver Injury,e [1–4]. Due to its lipophilicity, NO can pass easily into the intracellular area and affect cell metabolism. Thus, NO has a number of important biological functions as an intercellular and intracellular messenger [5]. Within the cell, NO activates soluble guanylate cyclase, which leads to an increa

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Oxidative Stress and Liver Injury by Environmental Xenobiotics,viz: ageing, inflammation, carcinogenesis, drug action, drug toxicity. defence against protozoa and many others. Moreover, oxidative damage to biological material is inflicted on compounds of all major chemical classes. It is mediated by reactive oxygen species (ROS). Oxygen radicals that are probab

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Hepatic Bilirubin Metabolism: Physiology and Pathophysiology,obin of senescent erythrocytes and the rest from ineffective erythropoiesis in the bone marrow (heme not used for hematopoiesis), and rapid hepatic metabolism of heme and hemoproteins such as cytochrome P450 [1]. Heme oxygenase is distributed in the liver, spleen, bone marrow, renal parenchyma, and