Titlebook: Liver Carcinogenesis; Methods and Protocol Guido Kroemer,Jonathan Pol,Isabelle Martins Book 2024 The Editor(s) (if applicable) and The Auth

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Single-Cell Characterization of the Tumor Ecosystem in Liver Cancer,th stromal and immune cells. Here we introduce the experimental protocol and computational methods for the single-cell study of liver cancer, which may be essential for a mechanistic understanding of the tumor ecosystem in liver cancer and further pave the way for developing novel therapeutics.

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1064-3745 ation advice from the experts.This volume discusses the latest advancements in modern methodologies used to study liver carcinogenesis. The first half of this book describes pertinent preclinical models of hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), established either through orthot

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A Mouse Model of Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma Induced by Western Dietintraperitoneal injections of carbon tetrachloride (CCl.) at a dose of 0.2 μL/g of body weight. The resulting phenotype, consisting in liver fibrosis and HCC, appeared within 24 weeks of diet/treatment initiation and presented similar histological and transcriptomic features as human NASH and NASH-d

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