Titlebook: Lithium and Cell Physiology; Ricardo O. Bach (President and Manager),Vincent S. Book 1990 Springer-Verlag New York Inc. 1990 cell.cell phy

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Lithium and Granulopoiesis: Mechanism of Action, depressive illnesses (1,2). Although lithium is the lightest metal known to exist in nature, it commonly is not considered to be one of the trace biological elements for mammalian cell systems. (This topic is discussed in detail in Chapter 1). However, it is a well-documented observation that lithi

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Does the Effect of Lithium on G-Proteins Have Behavioral Correlates?,d. Lithium has been shown to inhibit the accumulation of cyclic AMP stimulated by noradrenaline both in intact rat brain synaptosomes and in slices from rat cortex after in vitro or ex vivo administration (1,2). This effect occurs within the therapeutic range of the drug (0.7–1.5 mM) and has been pr

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The Interaction of Lithium with Magnesium-Dependent Enzymes,e on some enzymes relevant to neuronal processes. The interaction between Li. and Mg. is of interest since these two ions share a physiochemical similarity, and this is why it has been proposed that Li. exerts its mood-stabilizing effects or its toxic symptoms by interfering with Mg.-regulated proce

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Effects of Lithium on Essential Fatty Acid and Prostaglandin Metabolism,concentrations over the range of about 0.5 to 1.5 mM. In recent years, partly due to concerns about the toxic effects of higher levels, and partly due to recognition that the higher concentrations may not be required to achieve a therapeutic response, there has been a trend toward trying to maintain

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