Titlebook: Lithium Effects on Granulopoiesis and Immune Function; Arthur H. Rossof,William A. Robinson Book 1980 The Editor(s) (if applicable) and Th

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Lithium Carbonate in Medicine and Psychiatry-1800’s somewhat after it was discovered . 1817 by Arfvedson while working . the laboratory of Berzelius (Jefferson and Griest, 1977). Isolated from the mineral petalite and named lithium after the Greek word for stone, it was used ineffectively . the treatment of urinary calculi and gout based on t

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Biology of the Lithium Ion has also recently been used . the treatment of several other pathologic conditions such as schizophrenia, alcoholism, aggression, tardive dyskinesia, and Huntington’s chorea; however, its therapeutic efficacy . such conditions may be controversial. Although lithium is one of the most effective drug

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Release of Vitamin Binding Proteins from Granulocytes by Lithium: Vitamin B12 and Folate Binding Proty called our attention to the fact that some of his patients receiving lithium appeared to have mild leukocytosis. Joint investigation of this phenomenon with him confirmed that such was the case, and we learned that this phenomenon had been observed as far back as 1955 (Bille and Plum).

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The Effect of Lithium on Release of Granulocyte Colony Stimulating Activity ,n, 1971). Recent reports (Hammond and Dale, 1979) have suggested that Li may increase blood neutrophils . gray collie dogs with cyclic hematopoiesis and may attenuate the neutropenia induced by cyto-toxic chemotherapy (Stein et al., 1977; Fehir and Rossof, 1977; Lyman et al., 1978; Joyce and Cherven

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The Effect of Lithium Upon Granulocyte Production , and , in the Mouse (Risetto and Gassano, 1952; Mayfield and Brown, 1966; O’Connell, 1970; Murphy and Goodwin, 1971; Shopsin and Friedman, 1971). In 1973, Tisman .. postulated that the neutrophilia was due to an increase in the total blood granulocyte pool and also demonstrated augmentation of granulocyte proliferatio

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Effect of Lithium on Colony Formation and Production of Colony-Stimulating Factor1973), and yet has a stimulatory effect on granulopoiesis (Murphy .., 1971; Tisman .., 1973; Gupta .., 1976). Its potential as a therapeutic agent in Felty’s syndrome is now well known, and future uses remain to be clearly defined. Lithium has been reported to stimulate production of colony-stimulat

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