Titlebook: Lithium; Its Role in Psychiat Samuel Gershon,Baron Shopsin Book 1973 Plenum Press, New York 1973 Syndrom.diabetes.diagnosis.electroencephal

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Prophylactic Lithium Maintenance Treatment in Recurrent Endogenous Affective Disorders,reatment has been the subject of much debate, and a number of experimental designs were used to demonstrate its value. These studies have not only shed light on the clinical and pharmacological properties of the lithium ion; they have also provided new knowledge about the recurrent endogenous affective disorders.

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Lithium in Other Psychiatric Disorders,essive illness. These can be divided into controlled studies and anecdotal reports. We shall concentrate on a detailed review of controlled studies with the hope that briefer discussion of anecdotal reports may encourage definitive studies.

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A Narrative Account of Lithium Usage in Psychiatry,vský and Hanzliček in Prague are regular correspondents; Vartanian from Moscow visited me the very week that this chapter was started; and Gershon, another of the authors who published during those first 10 or 11 years, is an editor of this volume.

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,Pharmacology—Lithium Absorption, Distribution, Renal Handling, and Effect on Body Electrolytes,evels (Amdisen, 1969; Coppen and Bailey, 1970). It is possible that by avoiding extreme flings of blood lithium levels and by permitting more precise monitoring of serum lithium concentration, the incidence of lithium-induced side effects will eventually be reduced.

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,Pharmacology—Lithium Teratology,er guarantee that pregnant women and their fetuses will be exposed to lithium, and that the possible teratogenicity of the lithium ion will become a matter of importance for many patients, their families, and their physicians.

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The Affective Disorders: Clinical and Epidemiological Aspects,drugs, and in particular of lithium, has focused greater attention on the diagnosis, the symptomatology, and the clinical course of manic and depressive patients. New concepts and theories are emerging and older theories are being revised (Klerman, 1971).

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Lithium and Depression,pilepsy, and insomnia as well as claims that it functions as a tonic and sedative. Consequently, it is not surprising that the suggestion that lithium carbonate may be effective in the treatment of yet another clinical condition, depression, has been received with reservation.

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The Chemistry and Biochemistry of Lithium, consequence of the slow transformation of neutrons and protons to higher elements, which explains the low abundance of atoms of much higher atomic number, e.g., molybdenum, but is now known to be due to the path of nuclear transformations which produced large amounts of carbon and oxygen, but missed lithium (Fig. 1).