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Titlebook: Listeria monocytogenes: Pathogenesis and Host Response; Howard Goldfine,Hao Shen Book 2007 Springer-Verlag US 2007 Immunity.Listeria monoc

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书目名称Listeria monocytogenes: Pathogenesis and Host Response
编辑Howard Goldfine,Hao Shen
视频video
概述The first comprehensive volume on Listeria that can be marketed to microbiologists, immunologists, and food scientists
图书封面Titlebook: Listeria monocytogenes: Pathogenesis and Host Response;  Howard Goldfine,Hao Shen Book 2007 Springer-Verlag US 2007 Immunity.Listeria monoc
描述We are at the beginning of the third decade of studies at the molecular level on the pathogenesis of Listeria monocytogenes and the response of the host to its infections. It is a good time to survey the wealth of information that these studies have revealed and to think about perspectives for a more complete understanding of this important pathogen. During the past 20 years, L. mono- togenes has emerged from relative obscurity to being one of the most intensely studied bacterial pathogens. In the opening chapter, Daniel A. Portnoy provides a personal and historical account of the development of our understanding at the molecular level of invasion of the host cell, growth in the cytosol, and ce- to-cell spread by means of actin polymerization-powered motility. We are also fortunate to have contributions from Pascale Cossart and Werner Goebel and their colleagues. These pioneering investigators continue to make major cont- butions to the molecular description of almost every aspect of L. monocytogenes pathogenesis. All chapters in this book have been written by experts who have contributed widely to this field. We are extremely grateful for the efforts of all contributors who have p
出版日期Book 2007
关键词Immunity; Listeria monocytogenes; Mamma; Pathogene; biology; cell biology; host response; infections; physio
版次1
doihttps://doi.org/10.1007/978-0-387-49376-3
isbn_softcover978-1-4899-9267-3
isbn_ebook978-0-387-49376-3
copyrightSpringer-Verlag US 2007
The information of publication is updating

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Regulation of Listeria monocytogenes Virulence Genes,g ingestion by mammals. The bacterium makes the transition from outside environment to host via the coordinate regulation of virulence gene products that enable bacterial replication within host cells. PrfA is transcriptional activator that is required for the expression of nearly all identified . v
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Invasion of Host Cells by Listeria monocytogenes,of the internalin family of listerial surface proteins have been shown to be required for cellular invasion, subverting cellular functions and structures such as adherens junctions in the case of InlA, or the hepatocyte growth factor receptor signaling in the case of InlB. Additional noninternalin m
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Immune Evasion and Modulation by Listeria monocytogenes,o the recognition and elimination of this pathogen from the host. However, although . infection induces robust immune responses, the bacterium has evolved mechanisms to evade and modulate the immune response. Its intracellular niche allows it to evade several aspects of the innate and adaptive immun
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