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Titlebook: Liquid Chromatography in Clinical Analysis; Pokar M. Kabra,Laurence J. Marton Book 1981 Springer Science+Business Media LLC 1981 carbohydr

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Tricyclic Antidepressantsogous to many other drug substances, the tricyclic drugs exhibit clinical effectiveness within a defined therapeutic concentration range (.–.). Very recently, both Dito (.) and Orsulak and Schildkraut (.) have summarized the usefulness of measuring serum concentrations of these drugs. These authors
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Antineoplastic Drugs antineoplastic activity and obscure the relationships among drug serum levels and therapeutic benefits. Moreover, new agents for cancer chemotherapy are being introduced at a more rapid rate than for the treatment of other diseases, although the successful application of therapeutic drug-level moni
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Hypnotics and Sedativesdrugs, such as the opiates, represent less of a problem on a day-to-day basis than do overdoses of prescribed drugs, such as sedatives and hypnotics. Clinical signs and symptoms for a narcotic drug overdose are very distinct, and in the majority of cases can be easily recognized by the attending phy
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Toxicology Screenings and O’Brien (.) noted that prior to 1960, drug overdoses usually consisted of a single drug. However, three years later they observed that multiple drug overdoses had risen to 13% (.). Law (.) reported that out of 240 proven drug misuse cases observed in Suburban Hospital, Bethesda, Maryland, over
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Determination of Tyrosine and Tryptophan Metabolites in Body Ruids Using Electrochemical Detection tyrosine, serve as neurotransmitters in the central and peripheral nervous systems. Serotonin, a major metabolite of tryptophan, is a potent neurotransmitter and vasoconstrictor. Without doubt, these compounds have been some of the most intensely studied molecules in the last twenty years. One of t
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Proteinsive analyses must often be preceded by some purification step that separates the molecular species being examined from interfering materials. In the case of proteins, column liquid chromatography has been used extensively for these fractionations. With the advent of gel permeation, cation exchange,
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Bilirubin and Its Carbohydrate Conjugatese is a tetrapyrrolic macrocycle and plays a critical role in aerobic metabolism by reversibly binding oxygen in hemoglobin and myoglobin, and by serving as the active site in oxidation reactions catalyzed by hemoprotein enzymes. Important cyclic tetrapyrroles in nature related to heme are chlorophyl
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