| 书目名称 | Lipids in Protein Misfolding |
| 编辑 | Olga Gursky |
| 视频video | |
| 概述 | Explains how protein misfolding is an important biological phenomenon underlying over 20 major human diseases.Shows that Lipids importantly influence protein misfolding and amyloid diseases.Provides a |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | Protein conversion from a water-soluble native conformation to the insoluble aggregates and fibrils, which can deposit in amyloid plaques, underlies more than 20 human diseases, representing a major public health problem and a scientific challenge. Such a conversion is called protein misfolding. Protein misfolding can also involve errors in the topology of the folded proteins and their assembly in lipid membranes. Lipids are found in nearly all amyloid deposits in vivo, and can critically influence protein misfolding in vitro and in vivo in many different ways. This book focuses on recent advances in our understanding of the role of lipids in modulating the misfolding of various proteins. The main emphasis is on the basic biophysical studies that address molecular basis of protein misfolding and amyloid formation, and the role of lipids in this complex process. |
| 出版日期 | Book 2015 |
| 关键词 | amyloid formation; biophysical and structural approaches; molecular mechanisms of protein misfolding; p |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-17344-3 |
| isbn_softcover | 978-3-319-37205-1 |
| isbn_ebook | 978-3-319-17344-3Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 19:47:52
