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Titlebook: Lipid A in Cancer Therapy; Jean-François Jeannin Book 2010 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spr

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发表于 2025-3-21 17:42:12 | 显示全部楼层 |阅读模式
书目名称Lipid A in Cancer Therapy
编辑Jean-François Jeannin
视频video
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Lipid A in Cancer Therapy; Jean-François Jeannin Book 2010 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spr
描述.Cancer remains a major challenge for modern society. Not only does cancer rank among the first three causes of mortality in most population groups but also the therapeutic options available for most tumor types are limited. The existing ones have limited efficacy, lack specificity and their administration carry major side effects. Hence the urgent need for novel cancer therapies. One of the most promising avenues in research is the use of specific immunotherapy...The notion that the immune system may have important anti-tumor effects has been around for more than a century now. Every major progress in microbiology and immunology has been immediately followed by attempts to apply the new knowledge to the treatment of cancer. Progress has reached a point where it is well established that most cancer patients mount specific T cell responses against their tumors. The molecular identity of the antigens recognized by anti-tumor T cells has been elucidated and several hundreds of tumor-derived antigenic peptides have been discovered. Upon recognition of such peptides presented by self MHC molecules, both CD8 and CD4 T cells are activated, expand to high numbers and differentiate into eff
出版日期Book 2010
关键词Antigen; Biology; Cancer; Jeanin; Lipid; Medicine; Therapy
版次1
doihttps://doi.org/10.1007/978-1-4419-1603-7
isbn_softcover978-1-4614-2497-0
isbn_ebook978-1-4419-1603-7Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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Shoichi Kusumoto,Masahito Hashimoto,Kazuyoshi Kawahara
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Néjia Sassi,Catherine Paul,Amandine Martin,Ali Bettaieb,Jean-François Jeannin
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Cheryl E. Rockwell,David. C. Morrison,Nilofer Qureshi
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Interactions between Lipid A and Serum Proteins,f endotoxin (.)..There is a multitude of studies analyzing the interactions between serum proteins and endotoxins, however, with great differences in the source and quality of the endotoxins used. The number of studies dealing with chemically well defined endotoxin structures are quite limited. In a
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Lipid A-Mediated Tolerance and Cancer Therapy,ecular mechanism remains unclear. This may be due, in part, to differences in the experimental models used, the sources and types of microbes and microbial products studied, kinetics of responses, and/or other experimental conditions. Nonetheless, a number of different signaling pathways have been i
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