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Titlebook: Linkage Disequilibrium and Association Mapping; Analysis and Applica Andrew R. Collins Book 2007 Humana Press 2007 Allele.DNA.SNP.gene.gene

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etardant action. The results of studying the structure and composition of the products of thermolysis of intumescent components using the Fourier transform infrared spectroscopy, chromatography–mass spectrometry and scanning electron microscopy are summarized. As a result of the studies conducted by
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1064-3745 ed in tis complex research field.Cutting-edge analysis of th.As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In Linkage Disequilibrium and Association Mapping: Analysis and Applications, scientists from around the world,
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Linkage Disequilibrium and Association Mapping,recedented detail. This information not only provides a vital resource for the design and execution of powerful association-mapping studies, but opens new avenues of research into the genetic history of human populations and the effects of natural selection, mutation, and recombination on the genomic landscape.
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Avoiding False Discoveries in Association Studies,k for hypothesis testing and correction for multiple comparisons. We consider in detail the currently accepted strategies in linkage analysis. We then examine the underlying similarities and differences between linkage and association studies and document some of the most recent methodological developments for association mapping.
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Association Mapping Using Pooled DNA,locus association mapping, and a confirmation study. Software and an analysis of authentic data are presented. The strengths and weaknesses of pooled-DNA analyses, as well as possible future applications for this method, are discussed.
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Linkage Disequilibrium as a Tool for Detecting Signatures of Natural Selection,y fallen short of unambiguously distinguishing selection from other biological mechanisms. Contemporary genetic maps that describe LD in fine detail represent a much needed tool that can be exploited by researchers aiming to tease apart these opposing signals.
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