| 书目名称 | Ligand-Macromolecular Interactions in Drug Discovery | | 副标题 | Methods and Protocol | | 编辑 | Ana Cecília A. Roque | | 视频video | | | 概述 | Provides an easily accessible reference volume for the study of ligand-macromolecule interactions in the context of drug research written by leading researchers in the field.Details the principles of | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .Drug research has been greatly transformed by the “omics revolution” and advances in computational tools, combinatorial chemistry, and high throughput screening techniques (HTS). These implements have advanced the ability to identify target molecules that serve as points of attack for future medicines, the design and synthesis of potential lead compounds, and further characterization, screening, and assays for therapeutic efficacy and toxicity. In .Ligand-Macromolecular Interactions in Drug Discovery: Methods and Protocols., experts in the field highlight the main principles and methodologies currently utilized in the study of molecular interactions between compounds, either natural or synthetic, and complementary biological targets, within the scope of drug discovery. Beginning with a historical perspective of drug research focusing on the contribution of genomics, proteomics, high-throughput methods, and computational developments in drug discovery, the book then delves into highly detailed methods on topics such as NMR spectroscopy, compound library design and synthesis, chemical and biological microarrays, and many others. Written in the highly successful .Methods in Molecula | | 出版日期 | Book 2010 | | 关键词 | Biological microarrays; Compound libraries; Drug research and design; High-throughput methods; Proteins; | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-60761-244-5 | | isbn_softcover | 978-1-4939-6177-1 | | isbn_ebook | 978-1-60761-244-5Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2010 |
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发表于 2025-3-21 16:57:05
