| 书目名称 | Life-Span Extension | | 副标题 | Single-Cell Organism | | 编辑 | Christian Sell,Antonello Lorenzini,Holly M. Brown- | | 视频video | | | 概述 | Multidisciplinary, with viewpoints of experts studying the aging process in species ranging from yeast to man.Discusses identification of common pathways that modulate longevity.Provides overview of r | | 丛书名称 | Aging Medicine | | 图书封面 |  | | 描述 | .In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. In Life-Span Extension: Single-Cell Organisms to Man, the editors bring together a range of illuminating perspectives from researchers investigating the aging process in a variety of species. This novel work addresses the aging process in species ranging from yeast to man and, among other subjects, features detailed discussions of the naked mole-rat, an exceptionally long-lived rodent; the relationship between dietary factors/food restriction and aging; and an evolutionary view of the human aging process....Single mutations that extend life span have been identified in yeast, worms, flies, and mice, whereas studies in humans have identified potentially important markers for successful aging. At the same time, it has been discovered that the genes and pathways identified in these studies involve a surprisingly small set of conserved functions, most of which have been the focus of aging research for some time. For example, the mTOR pathway, a regulator of translation and protein synthesis, has been identified as a common longevity pathway in yeast and Caenorhabditis elegans. In mamm | | 出版日期 | Book 2009 | | 关键词 | Caenorhabditis elegans; Life span; Life-span extension; Longevity; Mammals; Markers; Neuroendocrine pathwa | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-60327-507-1 | | isbn_softcover | 978-1-61779-747-7 | | isbn_ebook | 978-1-60327-507-1 | | copyright | Humana Press 2009 |
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发表于 2025-3-21 16:53:25
