Titlebook: Levodopa-Induced Dyskinesia in Parkinson‘s Disease; Susan H. Fox,Jonathan M. Brotchie Book 2014 Springer-Verlag London 2014 Parkinson‘s di

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exclusice

,Features and Mechanisms of Diphasic Dyskinesia in Parkinson’s Disease,the beginning and at the end, but not at the peak, of the levodopa effect in long-term treated Parkinson’s disease patients. The most commonly affected subjects with this form of dyskinesia are those who have an early onset of the disease, approaching 20 % of globally treated parkinsonian patients.

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Dopamine Receptors and Levodopa-Induced Dyskinesia,physiology of L-3,4-dihydroxyphenylalanine (.-DOPA)-induced dyskinesias (LID) in parkinsonian patients and animal models. Altered dopaminergic neurotransmission in the basal ganglia are observed in LID. Two conditions are necessary for their appearance: (1) loss of DA in nigrostriatal pathway and (2

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