| 书目名称 | Leukocyte Recruitment, Endothelial Cell Adhesion Molecules, and Transcriptional Control | | 副标题 | Insights for Drug Di | | 编辑 | Tucker Collins | | 视频video | | | 图书封面 |  | | 描述 | The localized attachment of circulating leukocytes toendothelium has been recognized as the cellular hallmark of theinflammatory response. This adhesive interaction, a necessaryantecedent to the emigration of leukocytes from the blood into thetissues, is mediated by vascular adhesion molecules. .LeukocyteRecruitment, Endothelial Cell Adhesion. .Molecules andTranscriptional Control: Insights for Drug Discovery. outlines someof the cellular and molecular mechanisms of inflammation withcontributions from top researchers..This volume provides an overview of three of these endothelialadhesion molecules, as examples of key mediators of leukocyterecruitment. It reviews the structure and regulation of these cellsurface proteins and focus on the rapidly expanding field oftranscriptional regulation of these inducible proteins, and closeswith a discussion of drug discovery possibilities that target theregulation of leukocyte recruitment. .This book will be of interest for any researchers, in academia orindustry, looking for an overview of leukocyte recruitment or novelapproaches to drug discovery. | | 出版日期 | Book 2001 | | 关键词 | cell; gene expression; inflammation; protein; proteins; tissue; transcription | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4615-1565-4 | | isbn_softcover | 978-1-4613-5617-2 | | isbn_ebook | 978-1-4615-1565-4 | | copyright | Springer Science+Business Media New York 2001 |
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发表于 2025-3-21 18:30:16
