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Titlebook: Leukocyte Integrins in the Immune System and Malignant Disease; Bernhard Holzmann,Hermann Wagner Book 1998 The Editor(s) (if applicable) a

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书目名称Leukocyte Integrins in the Immune System and Malignant Disease
编辑Bernhard Holzmann,Hermann Wagner
视频videohttp://file.papertrans.cn/586/585307/585307.mp4
概述The book focuses on leukocyte integrins, in particular, on receptors of the alpha4 subfamily.
丛书名称Current Topics in Microbiology and Immunology
图书封面Titlebook: Leukocyte Integrins in the Immune System and Malignant Disease; Bernhard Holzmann,Hermann Wagner Book 1998 The Editor(s) (if applicable) a
描述Most lymphocytes recirculate throughout the body, migrating from blood through organized lymphoid tissues such as lymph nodes (LN) and Peyer‘s patches (PP), then to lymph and back to blood (GOWANS and KNIGHT 1964). Smaller numbers of lymphocytes migrate from blood to extranodal tissues such as pancreas and then through lymphatic vessels to LN (MACKAY et al. 1990). An important feature of this migration is the ability of lymphocytes to recognize and adhere to the surface of blood vessel endothelial cells before migrating through the vessel wall into surrounding tissue (CARLOS and HARLAN 1994; IMHOF and DUNON 1995; BUTCHER and PICKER 1996). Adhesion interactions of vascular endothelium with lymphocytes under flow or shear consist of at least four steps: (I) an initial transient sticking or rolling; (2) if the lymphocytes encounter appropriate activating or chemotactic factors in the local environment, rolling may be followed by a lymphocyte activation step that then leads to; (3) strong adhesion or sticking that may be followed by; (4) lym­ phocyte diapedesis into tissue (BUTCHER 1991; SHIMUZU et al. 1992; SPRINGER 1994; BARGATZE et al. 1995). Specific lymphocyte and endothelial adhe
出版日期Book 1998
关键词Activation; T cell; cancer; cell; hematopoiesis; immune system; inflammation; inflammatory response; lymphom
版次1
doihttps://doi.org/10.1007/978-3-642-71987-5
isbn_softcover978-3-642-71989-9
isbn_ebook978-3-642-71987-5Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
The information of publication is updating

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Organ-Specific Requirements for Cell Adhesion Molecules During Lymphoma Cell Dissemination,t cell lodgment in organ parenchyma (a process known as cell homing), and cell migration on extracellular matrix (ECM) (. and . 1992; . and . 1992; . et al. 1992; . 1994; . and . 1995). Three pairs of adhesion receptor and counterreceptor families are implicated in the interaction between leukocytes
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,The Ups and Downs of α2β1-Integrin Expression: Contributions to Epithelial Cell Differentiation and all redundancy since each receptor may mediate distinct post-receptor occupancy events such as cell differentiation (. et al. 1987; . and . 1991), alteration in gene expression (. et al. 1989; . and . 1992), ion fluxes through membrane channels (. and . 1994), and regulation of tumor progression, i
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Book 1998environment, rolling may be followed by a lymphocyte activation step that then leads to; (3) strong adhesion or sticking that may be followed by; (4) lym­ phocyte diapedesis into tissue (BUTCHER 1991; SHIMUZU et al. 1992; SPRINGER 1994; BARGATZE et al. 1995). Specific lymphocyte and endothelial adhe
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M. Isobe,J. Hori,J. Suzuking examined at ITS ’98 include: Web based tutoring systems, deploying ITS in the real world, tutoring and authoring tools, architectures, and knowledge structure and representation.978-3-540-64770-6978-3-540-68716-0Series ISSN 0302-9743 Series E-ISSN 1611-3349
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0070-217X ocyte activation step that then leads to; (3) strong adhesion or sticking that may be followed by; (4) lym­ phocyte diapedesis into tissue (BUTCHER 1991; SHIMUZU et al. 1992; SPRINGER 1994; BARGATZE et al. 1995). Specific lymphocyte and endothelial adhe978-3-642-71989-9978-3-642-71987-5Series ISSN 0070-217X Series E-ISSN 2196-9965
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