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Titlebook: Leukocyte Adhesion Molecules; Proceedings of the F Timothy A. Springer (Associate Professor),Donald C Conference proceedings 1990 Springer-

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书目名称Leukocyte Adhesion Molecules
副标题Proceedings of the F
编辑Timothy A. Springer (Associate Professor),Donald C
视频videohttp://file.papertrans.cn/586/585306/585306.mp4
图书封面Titlebook: Leukocyte Adhesion Molecules; Proceedings of the F Timothy A. Springer (Associate Professor),Donald C Conference proceedings 1990 Springer-
描述Leukocyte adhesion molecules promise to be highly effective as antigens in the antibody-directed leucocyte elimination treatment prior to grafting or in cases of acute and chronic inflammatory disease. This comprehensive review of contemporary research provides thorough discussions of the structure of these molecules, their .in vitro .function, and the role that they play .in vivo. as evidenced by results shown in inflammatory models where antibodies against these molecules are given to inhibit their function. The blend of basic science and clinical applications provides clear evidence of the biological relevance of cell-cell interactions and the many potential clinical dividends afforded by understanding the molecular basis of cell adhesion.
出版日期Conference proceedings 1990
关键词Antigen; T cell; cell; immunosuppression; lymphocytes; receptor
版次1
doihttps://doi.org/10.1007/978-1-4612-3234-6
isbn_softcover978-1-4612-7927-3
isbn_ebook978-1-4612-3234-6
copyrightSpringer-Verlag New York Inc. 1990
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书目名称Leukocyte Adhesion Molecules影响因子(影响力)




书目名称Leukocyte Adhesion Molecules影响因子(影响力)学科排名




书目名称Leukocyte Adhesion Molecules网络公开度




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书目名称Leukocyte Adhesion Molecules读者反馈学科排名




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Mechanism Regulating Recruitment of CD11b/CD18 to the Cell Surface is Distinct From That Which Induc8, the common 95 kD beta subunit (.2) abolish neutrophil aggregation (2); (ii) several of the MAb to CD11b, the 165 kD alpha subunit (also referred to as αM, CR3, or MAC-1 inhibit this response (2,3); and (iii) neutrophils from individuals genetically deficient in these molecules cannot be stimulated to aggregate (4).
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ere antibodies against these molecules are given to inhibit their function. The blend of basic science and clinical applications provides clear evidence of the biological relevance of cell-cell interactions and the many potential clinical dividends afforded by understanding the molecular basis of cell adhesion.978-1-4612-7927-3978-1-4612-3234-6
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CD18 Dependence of Primate Eosinophil Adherence In Vitroedictive of an intense immediate response to inhaled antigen (6). Additionally, chronic airway eosinophilia in monkeys, either idiopathic (7) or induced by chronic antigen exposure (8), is associated with marked airway hyperresponsiveness to inhaled methacholine.
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