| 书目名称 | Leucine-Rich Repeat Kinase 2 (LRRK2) |
| 编辑 | Hardy J. Rideout |
| 视频video | |
| 概述 | Thorough overview of the current state of knowledge on LRRK2.Discussed the links between LRRK2 mutations and Parkinson‘s Disease.Explores what we know about the normal function of LRRK2.Includes suppl |
| 丛书名称 | Advances in Neurobiology |
| 图书封面 |  |
| 描述 | This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson‘s Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration. |
| 出版日期 | Book 2017 |
| 关键词 | GTPase; Parkinson‘s Disease; kinase; neurodegeneration; signaling |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-49969-7 |
| isbn_softcover | 978-3-319-84287-5 |
| isbn_ebook | 978-3-319-49969-7Series ISSN 2190-5215 Series E-ISSN 2190-5223 |
| issn_series | 2190-5215 |
| copyright | Springer International Publishing AG 2017 |
发表于 2025-3-21 18:49:49
