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Titlebook: Lectins and Glycoconjugates in Oncology; Hans-Joachim Gabius,Gero Arno Nagel Conference proceedings 1988 Springer-Verlag Berlin Heidelberg

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Endogenous Lectins of Myeloid and Tumor Cells: Characterization and Biological Implications,specific lectin of 3LL cells and by the α -L-Fuc specific lectin of lung cells. Monocytes and macrophages can be rendered tumoricidal by using neoglycoproteins carrying muramyldipeptide. This activator-neoglycoprotein conjugate allows to kill tumor cells . and . and to eradicate metastases in 3LL tu
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Gangliosides in Recognitive Cell Interactions and Carbohydrate-Mediated Biosignalling, formation) of canine kidney cells, MDCK (Rodrig et al. 1987). Thus, gangliosides concern with a certain important aspect of the modulation of cell growth and differentiation, which seem to be carried out by a carbohydrate-mediated biosignalling in cell surface membranes.
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Prospects for the Use of Immunotoxins Against Solid Tumour Metastases: Studies in a Syngeneic Rat MImmunotoxins (IT) constructed by coupling bacterial exotoxins or certain plant lectins to monoclonal antibodies (MAbs) with specificity for epitopes uniquely or preferentially expressed on tumour cells have been shown to exert remarkable degrees of cytotoxicity in vitro (Thorpe 1985, Neville 1986).
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Detection of Endogenous Sugar Binding Proteins in Malignant Tumors Especially in Human Breast CanceFrom the pathologist’s point of view the biological significance of lectins has been discussed intensively for the first time when a correlation of steroid receptor status to special lectin equipment could be demonstrated (KLEIN et al. 1981; LEATHEM et al. 1983).
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,Immunomodulation by Endogenous ß-Galactoside-Specific Lectins,The preceding contribution emphasized the role of a plant lectin, the ß-galactoside-specific lectin from mistletoe in mediation of immunomodulatory effects in the rabbit.
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